Escherichia coli ST410 lineage is classified as an international high-risk clone owing to its capacity to cause recurrent infections and its high transmissibility. Extended-spectrum ß-lactamase (ESBL)-producing E. coli ST410 is an extraintestinal pathogen that has been reported worldwide, being associated with resistance to extended-spectrum cephalosporins, fluoroquinolones and carbapenems . Multidrug-resistant (MDR) bacteria have generated a great threat to public health and have been reported in different spheres (e.g. human, animal, food and the environment). To the best of our knowledge, this study reports for the first time the occurrence of MDR CTX-M-8-producing E. coli in a captive elephant (Loxodonta africana), raising an alert about the emergence of ESBL producers in zoo animals.
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